Department of Molecular Biology and Genetics
Department of Molecular Biology and Genetics
Department of Molecular Biology and Genetics
Molecular Biology and Genetics is a rapidly evolving discipline that forms the foundation of modern biomedical sciences. It focuses on understanding the molecular mechanisms governing life processes, genetic inheritance, gene regulation, cellular communication, and disease pathogenesis. Advances in molecular biology, genomics, proteomics, bioinformatics, and biotechnology have revolutionized healthcare by enabling precision medicine, molecular diagnostics, targeted therapeutics, and personalized treatment strategies.
Mission: MPhil Molecular Biology and Genetics
The MPhil Molecular Biology and Genetics program aims to develop competent educators, researchers, and professionals with advanced knowledge and practical expertise in molecular biology, genetics, genomics, and bioinformatics. The program prepares graduates to teach undergraduate and postgraduate students, conduct independent research, and apply modern molecular technologies to address emerging challenges in biomedical sciences, biotechnology, and healthcare.
The program is committed to promoting scientific excellence, ethical research practices, critical thinking, and lifelong learning while encouraging interdisciplinary research that contributes to improving human health and advancing biomedical sciences at national and international levels.
Courses
The MPhil curriculum provides advanced theoretical knowledge and practical training in molecular biology, genetics, genomics, proteomics, computational biology, and bioinformatics. Students develop a comprehensive understanding of the molecular basis of inheritance, gene expression and regulation, cell signaling pathways, protein biology, and the computational approaches used to analyze biological data.
The program follows a progressive structure beginning with the molecular mechanisms of inheritance and gene regulation, followed by advanced concepts in cell signaling, proteomics, computational biology, and bioinformatics programming. Students are also exposed to emerging areas through elective courses including Recombinant DNA Technology, Cancer Genetics, Epigenetics, Evolutionary Genetics, DNA Fingerprinting, and Microbial Genetics.
Teaching and learning are supported through interactive lectures, laboratory practicals, computational exercises, journal clubs, seminars, workshops, and supervised research. The curriculum emphasizes experimental design, scientific writing, critical appraisal of published literature, and the application of advanced molecular and computational techniques to contemporary biomedical research.
Specialty Courses in MPhil Molecular Biology and Genetics
The specialty courses are designed in a stepwise manner and include:
Molecular Basis of Inheritance
Gene Expression and Regulation
Cell Signaling
Principles of Proteomics
Computational Biology
Programming in Bioinformatics
Elective courses include Recombinant DNA Technology, Cancer Genetics, Epigenetics, Evolutionary Genetics, DNA Fingerprinting, Microbial Genetics, Database and Web Designing, and Research Techniques & Basic Instrumentation. Journal club discussions, seminars, literature review, synopsis writing, and research workshops are integrated throughout the program to strengthen scientific reasoning, analytical skills, and independent research capability.
PhD Molecular Biology and Genetics
Department of Molecular Biology and Genetics
The PhD Molecular Biology and Genetics program is designed to develop independent scientists capable of conducting innovative and impactful research in molecular biology, genetics, genomics, bioinformatics, and biotechnology. The program emphasizes original research that advances scientific knowledge and contributes to solving complex biomedical and healthcare challenges through molecular and computational approaches.
Mission: PhD Molecular Biology and Genetics
The PhD program aims to produce highly skilled researchers, academicians, and scientific leaders capable of conducting internationally competitive research and translating scientific discoveries into practical applications. The program fosters innovation, interdisciplinary collaboration, research integrity, and lifelong learning while contributing to national and global priorities in biomedical sciences.
Program Overview
The PhD curriculum provides advanced training in molecular genetics, functional genomics, bioinformatics, computational biology, precision medicine, molecular diagnostics, and translational research. Scholars undertake original research using contemporary molecular, genomic, and computational technologies while developing expertise in experimental design, advanced laboratory techniques, data analysis, scientific communication, grant writing, and publication in peer reviewed journals.
The program encourages interdisciplinary and collaborative research in emerging fields such as cancer genomics, epigenetics, recombinant DNA technology, systems biology, artificial intelligence in life sciences, and precision medicine. Through seminars, journal clubs, workshops, and research presentations, scholars develop the critical thinking, leadership, and communication skills required for successful careers in academia, research institutions, biotechnology, pharmaceutical industries, and healthcare.
Research
Research and Training
The PhD program provides an intellectually stimulating research environment where scholars work closely with experienced faculty to undertake independent, high quality research. Emphasis is placed on innovation, scientific rigor, ethical conduct, international collaboration, and dissemination of research through high impact publications and scientific conferences. Graduates are expected to make significant contributions to biomedical research and advance molecular sciences through discovery, innovation, and translational applications.
Publications
- Ghrelin as a Candidate Molecule in Translational Pharmacology: Physiopharmacological Actions, Therapeutic Pros and Cons, and Delivery Challenges — Syed Murtaza Shah Bukhari, Mohsin Shah, Roshan Ali, Najeeb Ur Rehman, Pervaiz Ahmad, Fawad Ali Shah , Toxicology and Applied Pharmacology (2026) — Dr. Roshan Ali
- Knowledge, Attitude, and Practice Regarding Cardiovascular Diseases Among Primary and Secondary School Teachers: A Cross-Sectional Study — Shafaat Hussain, Roshan Ali2, Kashif Anar, Sayed Hadi Hussain, Seema Jamshid , Journal of Medical & Health Sciences Review (2026) — Dr. Roshan Ali
- Structural dynamics of glycosylated isoforms of Glycodelin: a comparative study through molecular dynamics simulation — Muhammad Shoaib, Mujeeb Alam Khan, Muhammad Idrees*, Roshan Ali4, Muhammad Waqas Luqman , Khyber Medical University Journal (2025) — Dr. Roshan Ali
- The Escherichia coli zinc exporter ZitB of the Cation Diffusion Facilitator (CDF) protein family: Properties, cloning, amplified expression, purification — Muhammad Ali, Roshan Ali2, Israr Ali Khan, Irshad Ahmad, Nighat Nawaz, Simon G Patching , Sch Int J Biochem 8(2) 50-65 (2025) (IBMS-Int) (2025) — Dr. Roshan Ali
- Expression Analysis of miR-132, miR-182, miR-124, miR-let7b and miR-let7c in Patients with Depression — Shamaila Wadud, Sadia Fatima, Rubina Nazli, Roshan Ali, Muhammad Irfan , Kurdish Studies 12(5) 253-257 (2024) (IBMS-Int (2024) — Dr. Roshan Ali
- Development and characterization of chitosan and chondroitin sulfate based hydrogels enriched with garlic extract for potential wound healing/skin regeneration applications — Fatima Masood, Muhammad Atif Makhdoom, Iftikhar Ahmed Channa, Sadaf Jamal Gilani, Ahmad Khan, Rabia Hussain, Syeda Ammara Batool, Kiran Konain, Saeed Ur Rahman, Abdul Wadood, May Nasser bin Jumah, Muhammad Atiq Ur Rehman (2022) — Ms. Kiran Konain
- Biomarker-guided drug repurposing and molecular validation of angiotensin-2 receptor type-1 in brain tumor — Konain K, Faheem M, Ullah K, Ayub S, Ahmed J, Huma Z, Javed A, Khan T, Hussain D, Khan IN (2023) — Ms. Kiran Konain
- Curcumin-Loaded Nanofibrous Matrix Accelerates Fibroblast Cell Proliferation and Enhances Wound Healing via GSK3-β Inhibition — 4. Konain, K.; Saddique, N.; Samie, M.; Rahman, Z.U.; Farid, S.; Hameed, S.; Mirza, M.R.; Wu, W.; Woo, K.M.; Arany, P.R.; et al , J. Compos. Sci (2023) — Ms. Kiran Konain
- Tideglusib-incorporated nanofibrous scaffolds potently induce odontogenic differentiation — Tabassum N, Khalid S, Ghafoor S, Woo KM, Lee EH, Samie M, Konain K, Ponnusamy S, Arany P, Rahman SU , Journal of Biomaterials Applications (2023) — Ms. Kiran Konain
- Hydrothermal synthesis of carbon dots incorporated in magnetite iron oxide nanoparticles for potential targeted brain cancer therapy: In-Vitro Study — Zahida Yaqoob, Syeda Ammara Batool, Muhammad Abdul Basit, Kiran Konain, Rizwan Ahmed Malik, Saeed Ur Rehman, Syed Wilayat Hussain, Hussein Alrobei, Muhammad Atiq Ur Rehman , Materials Chemistry and Physics (2024) — Ms. Kiran Konain
- Advanced 3D biomimetic scaffolds with bioactive glass and bone-conditioned medium for enhanced osteogenesis — Shazia Hameed, Saeed Ur Rahman, Kiran Konain, Muhammad Samie, Sajida Farid, Jeevithan Elango, Syed Rashid Habib, Kyung Mi Woo, Praveen R Arany , Biomaterials Advances (2025) — Ms. Kiran Konain
- Arabinoxylan-Incorporated Poly (ε-caprolactone) Nanofiber Matrix Promote Fibroblast Cells Adhesion and Proliferation — Kiran Konain, Sajida Farid, Shazia Hameed, Fozia Rehman, Muhammad Samie, Faiza Sharif, Muhammad Zaman, Syed Rashid Habib, Jeevithan Elango, Saeed Ur Rahman , BioNanoScience (2025) — Ms. Kiran Konain
- Frequency of Staphylococcus Aureus Infection Associated with Femoral Double Lumen Catheter in Kidney Failure Patients — IHTISHAM Khan, MUHAMMAD Faizan, WAFA Naeem, MUHAMMAD Zubair, AHMAD SHAMIM Khan, SYED LUQMAN Shuaib, SADIR Zaman , Pak J Med Health Sci (2022) — Dr. Wafa Naeem
- Laboratory biosafety measures of SARS-CoV-2 at containment level 2 with particular reference to its more infective variants — Wafa Naeem, Habiba Zeb, Muhammad Ibrahim Rashid , Biosafety and Health (2022) — Dr. Wafa Naeem
- Optimization of colony polymerase chain reaction for the 16S rRNA of different strains of Escherichia coli — A Ullah, A Bashir, B Rehman, W Naeem, S Zara Shah , Innovare J Life Sci (2023) — Dr. Wafa Naeem
- Mutational insights and in silico characterization of NEK family kinases in OSCC patients from the Pakistani population — Fouzia Nawab, Wafa Naeem, Sadia Fatima, Muhammad Uzair Khan, Aamir Mehmood, Sadia Nawab, Ishaq Khan, Haseena Nawaz, Hilal Ahmad, Ali Talha Khalil, Ishtiaq Ahmad Khan, Muhammad Irfan, Mohammed Alorini, Syed Ali Khurram, Asif Ali , Frontiers in Bioinformatics (2025) — Dr. Wafa Naeem
- Profiling genetic mutations in the DNA damage repair genes of oral squamous cell carcinoma patients from Pakistan — Wafa Naeem, Fouzia Nawab, Muhammad Tahir Sarwar, Ali Talha Khalil, Dalia Ali Gaber, Hilal Ahmad, Muhammad Fazeel, Mohammed Alorini, Ishtiaq Ahmad Khan, Muhammad Irfan, Muslim Khan, Syed Ali Khurram, Asif Ali , Scientific Reports (2025) — Dr. Wafa Naeem
- Exploring the mutational spectrum of key kinase genes PIK3CA, BRAF, EGFR, ALK and ROS1 in oral squamous cell carcinoma — Fouzia Nawab, Wafa Naeem, Sadia Fatima, Asif Ali, Ali Talha Khalil, Aamir Mehmood, Muhammad Fazeel, Hilal Ahmad, Mohammed Alorini, Muslim Khan, Ishtiaq Ahmad Khan, Muhammad Irfan, Syed Ali Khurram , BMC cancer (2025) — Dr. Wafa Naeem
- Prognostic value of VEGF-A expression and mutations in oral squamous cell carcinoma — Benish Aleem, Asif Ali, Wafa Naeem, Fouzia Nawab, Muslim Khan, Taj Ali Khan, Samrina Mohammad, Ihtisham Ul Haq, Haseena Nawaz, Muhammad Imtiaz, Ali Khurram , Arab Journal of Basic and Applied Sciences (2025) — Dr. Wafa Naeem
- EXPRESSION OF ANTI-PROGRAMMED DEATH-LIGAND 1 AND ANTI-CLUSTER OF DIFFERENTIATION 8 ANTIBODIES IN ORAL SQUAMOUS CELL CARCINOMA: A CROSS-SECTIONAL STUDY — Suman Mohammad Wazir, Mehreen Raziq, Saleha Saeed, Maria Ilyas, Hoor Maryam, Wafa Naeem , Genetics and Molecular Research (2026) — Dr. Wafa Naeem
Student life and achievements information is being updated.
Facilities information is being updated.
Contact
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