Dr. Najeeb Ullah

Biography

Previously, I have worked as an Assistant Professor and am currently working as an Associate Professor in the department of anatomy, Institute of Basic Medical Sciences, Khyber Medical university. As a founding faculty of the Institute of Basic Medical Sciences , I have played an important role in establishment of department and institute and defining its mission to promote quality in basic medical research

My academic profile as faculty member in biomedical, transnational, cellular and molecular neuroscience is characterized by a strong dedication to both teaching and research. During my Postdoctoral training, I have developed and strengthen my skills in both teaching and research and shared my experiences with peers and actively contributed to the development of research culture at Khyber medical University and others institutes.

My teaching interest includes Neurobiology, Developmental Biology, Cellular Biology, Genetics/Molecular Biology and Research Techniques. I mainly focused on providing students with comprehensive understanding of the principle of the structural and functional changes of the cells and living system, through combination of class lecture, assignments, laboratories exercise and interactive session.

My research is primarily focuses on studying the underlying mechanism of oxidative stress, neurodevelopmental, neuropsychological and age-related disorders. Specifically, I am interested to explore potential targets for intervention to develop novel neurotherpeutics to address these conditions by elucidating the cell signaling pathways of neuronal cells and system. Furthermore, I am also interested to investigate the complex cell signaling pathways that regulate cell death and cell survival of the living systems.

I have published many valuable research articles in well reputed international journals, which contributed significantly at international and national level to the scientific community. Based on my performance and research outcome, the Higher Education Commission of Pakistan awarded me two research grants. Recently one of our applied research has been selected for its innovation and impact, resulting in the patenting of our finding in the united State of America (USA).

Furthermore, I have established collaborations with researchers both nationally and internationally. Additionally, I have served as the member of the Graduate studies committee of various institute and reviewer for reputable scientific journals, projects in Pakistan and abroad.

Research Interests

Research interests will be added here.

Publications

• Effect of the co-administration of vitamin C and vitamin E on tyrosine hydroxylase and Nurr1 expression in the prenatal rat ventral mesencephalon — Hae Young Lee, Nibedita Naha, Najeeb Ullah, Guang Zhen Jin, Il Keun Kong, Phil Ok Koh, Hwan Hoo Seong, Myeong Ok Kim , Journal of Veterinary Medical Science (2008)
• Vitamin-C protects ethanol induced apoptotic neurodegeneration in postnatal rat brain — Muhammad Imran Naseer, U Najeeb, U Ikram, H Zubair Hassan, MBC Yang, Myeong Ok Kim , Pak J Med Sci (2009)
• PHORBOL MYRISTATE ACETATE (PMA) INDUCED MEGAKARYOCYTIC DIFFERENTIATION OF K562 CELLS FROM HUMAN CHRONIC MYELOGENOUS LEUKAEMIA PATIENT — Muhammad Imran Naseer, Hassan Zubair, Najeebullah Ikramullah, Hae Young Lee, Myeong Ok Kim , Pak J Med Sci April-June (2010)
• siRNA‐mediated GABAB receptor at early fetal rat brain upon acute and chronic ethanol exposure: Down regulation of PKA and p‐CREB expression — MI Naseer, HY Lee, N Ullah, I Ullah, MS Park, MO Kim , Synapse (2011)
• Vitamin C protects against ethanol and PTZ‐induced apoptotic neurodegeneration in prenatal rat hippocampal neurons — MI Naseer, N Ullah, I Ullah, PO Koh, HY Lee, MS Park, MO Kim , Synapse (2011)
• Neuroprotective effect of vitamin C against PTZ induced apoptotic neurodegeneration in adult rat brain. — Muhammad Imran Naseer, Ikram Ullah, Najeeb Ullah, YOUNG LEE HAE, CHEON EUN WOO, Jongil Chung, OK KIM MYEONG , Pakistan journal of pharmaceutical sciences (2011)
• Protective effect of pyruvate against ethanol-induced apoptotic neurodegeneration in the developing rat brain — Najeeb Ullah, Muhammad Imran Naseer, Ikram Ullah, Hae Young Lee, Phil Ok Koh, Myeong Ok Kim , Neuropharmacology (2011)
• Neuroprotection with metformin and thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons — Ikram Ullah, Najeeb Ullah, Muhammad Imran Naseer, Hae Young Lee, Myeong OK Kim , BMC neuroscience (2012)
• Amorphous amphiphilic P(3HV-co-4HB)-b-mPEG block copolymer synthesized from bacterial copolyester via melt transesterification: Nanoparticle preparation, cisplatin-loading for cancer therapy and in vitro evaluation — Mohsin Shah, Najeeb Ullah, Mun Hwan Choi, Myeong Ok Kim, Sung Chul Yoon , European Journal of Pharmaceutics and Biopharmaceutics (2012)
• Protective function of nicotinamide against ketamine-induced apoptotic neurodegeneration in the infant rat brain — Najeeb Ullah, Ikram Ullah, Hae Young Lee, Muhammad Imran Naseer, Park Moon Seok, Jawad Ahmed, Myeong Ok Kim , Journal of Molecular Neuroscience (2012)
• Decreased GABABR expression and increased neuronal cell death in developing rat brain after PTZ-induced seizure — Muhammad Imran Naseer, Ikram Ullah, Mohammed H Al-Qahtani, Sajjad Karim, Najeeb Ullah, Shakeel Ahmed Ansari, Myeong Ok Kim, Fehmida Bibi , Neurological Sciences (2013)
• Neuroprotective profile of pyruvate against ethanol-induced neurodegeneration in developing mice brain — Najeeb Ullah, Muhammad Imran Naseer, Ikram Ullah, Tae Hyun Kim, Hae Young Lee, Myeong Ok Kim , Neurological Sciences (2013)
• Caffeine prevents d-galactose-induced cognitive deficits, oxidative stress, neuroinflammation and neurodegeneration in the adult rat brain — Faheem Ullah, Tahir Ali, Najeeb Ullah, Myeong Ok Kim , Neurochemistry international (2015)
• Current and emerging biomarkers in tumors of the central nervous system: Possible diagnostic, prognostic and therapeutic applications — Kulvinder S. Saini. Ishaq N. Khan, Najeeb Ullah, Deema Hussein , Seminars in Cancer Biol. (2017)
• Neurological enhancement effects of melatonin against brain injury-induced oxidative stress, neuroinflammation, and neurodegeneration via AMPK/CREB signaling — Shafiq Ur Rehman, Muhammad Ikram, Najeeb Ullah, Sayed Ibrar Alam, Hyun Young Park, Haroon Badshah, Kyonghwan Choe, Myeong Ok Kim , Cells (2019)
• Melatonin act as an antidepressant via attenuation of neuroinflammation by targeting Sirt1/Nrf2/HO-1 signaling — T Ali, Q Hao, N Ullah, SU Rahman, FA Shah, K He, C Zheng, W Li, I Murtaza, Y Li, Y Jiang, Z Tan, S Li , Frontiers in molecular neuroscience (2020)
• Potent natural antioxidant carveol attenuates MCAO-stress induced oxidative, neurodegeneration by regulating the Nrf-2 pathway — Imran Malik, Fawad Ali Shah, Tahir Ali, Zhen Tan, Abdullah Alattar, Najeeb Ullah, Arif-ullah Khan, Reem Alshaman, Shupeng Li , Frontiers in neuroscience (2020)
• Association of acyl-ghrelin with posttraumatic stress disorder in adolescents who experienced severe trauma — Muhammad Omar Malik, Mohsin Shah, Muhammad Irfan ul Akbar Yousufzai, Najeeb Ullah, JoColl A Burgess, Ki Ann Goosens , JAMA Network Open (2020)
• Antidepressant-like effect of ethanol in mice forced swimming test is mediated via inhibition of NMDA/nitric oxide/cGMP signaling pathway — Muhammad Imran Khan, Vahid Nikoui, Aamir Naveed, Faiza Mumtaz, Hamid Zaman, Adnan Haider, Waqar Aman, Abdul Wahab, Shahid Niaz Khan, Najeeb Ullah, Ahmad Reza Dehpour , Alcohol (2021)
• Multiple Primary Spinal Extradural Hydatid Cysts: A Clinical Case Report — Nuzhat Sultana, Muhammad Kamran Ameer, Masroor Hassan, Adnan Khan and Najeeb Ullah , American Journal of Biomedical Science & Research (2024)
• Correction to: Neuroprotective profile of pyruvate against ethanol-induced neurodegeneration in developing mice brain — Najeeb Ullah, Muhammad Imran Naseer, Ikram Ullah, Tae Hyun Kim, Hae Young Lee, Myeong Ok Kim , Neurological Sciences (2024)